Jean-Claude Dussaule Selected Research

Inflammation (Inflammations)

5/2017	NFκB-Induced Periostin Activates Integrin-β3 Signaling to Promote Renal Injury in GN.
1/2017	The Role of Discoidin Domain Receptor 1 in Inflammation, Fibrosis and Renal Disease.
2/2016	Protective effects of genetic inhibition of Discoidin Domain Receptor 1 in experimental renal disease.
7/2015	Activation of Notch3 in Glomeruli Promotes the Development of Rapidly Progressive Renal Disease.
8/2014	Inhibition of periostin expression protects against the development of renal inflammation and fibrosis.
4/2013	Renin inhibition reverses renal disease in transgenic mice by shifting the balance between profibrotic and antifibrotic agents.
11/2012	Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury.
6/2012	Thrombospondin-1 plays a profibrotic and pro-inflammatory role during ureteric obstruction.
1/2012	[Chronic kidney disease, new therapeutic approaches].
7/2011	Discoidin domain receptor 1 is a major mediator of inflammation and fibrosis in obstructive nephropathy.

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Jean-Claude Dussaule Research Topics

Disease

26	Fibrosis (Cirrhosis) 10/2017 - 03/2001
17	Hypertension (High Blood Pressure) 10/2014 - 03/2001
13	Inflammation (Inflammations) 05/2017 - 12/2006
11	Proteinuria 10/2017 - 11/2003
11	Chronic Renal Insufficiency 07/2015 - 07/2009
3	Hypoxia (Hypoxemia) 01/2020 - 11/2005
3	Ischemia 01/2020 - 06/2016
3	Ureteral Obstruction 02/2016 - 06/2012
3	Glomerulonephritis 10/2012 - 07/2011
3	Sclerosis 12/2006 - 03/2001
2	Hypertensive Nephropathy 06/2016 - 01/2012
2	Disease Progression 07/2015 - 01/2012
2	Kidney Diseases (Kidney Disease) 01/2012 - 07/2007
2	Renal Insufficiency (Renal Failure) 09/2011 - 01/2008
2	Sickle Cell Anemia (Hemoglobin S Disease) 05/2008 - 11/2005
1	Edema (Dropsy) 01/2022
1	Acute Kidney Injury (Acute Renal Failure) 01/2022
1	COVID-19 01/2021
1	Reperfusion Injury 01/2020
1	Tremor (Tremors) 10/2012
1	Fragile X Tremor Ataxia Syndrome 10/2012
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2012
1	Hypertrophy 07/2009
1	Vascular Diseases (Vascular Disease) 07/2007
1	Vascular Remodeling 07/2007
1	Hemorrhage 09/2006
1	Coronary Artery Disease (Coronary Atherosclerosis) 09/2006
1	Cicatrix (Scar) 11/2005
1	Dehydration (Water Stress) 11/2005
1	Nephrogenic Diabetes Insipidus 11/2005
1	Chronic Kidney Failure (Chronic Renal Failure) 02/2004

Drug/Important Bio-Agent (IBA)

9	Angiotensin IIIBA 01/2021 - 03/2001
8	CollagenIBA 06/2012 - 03/2001
7	NG-Nitroarginine Methyl Ester (L-NAME)IBA 06/2016 - 03/2001
6	CreatinineIBA 10/2017 - 05/2003
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2003
5	Discoidin Domain Receptor 1IBA 01/2017 - 12/2006
5	ReninIBA 04/2013 - 01/2002
4	PeriostinIBA 01/2020 - 01/2012
4	AngiotensinsIBA 01/2012 - 03/2001
4	Endothelin Receptor AntagonistsIBA 01/2012 - 03/2001
4	ErbB Receptors (EGF Receptor)IBA 09/2011 - 05/2004
3	Connexin 43 (Connexin43)IBA 10/2017 - 07/2011
3	Extracellular Matrix ProteinsIBA 06/2011 - 07/2007
3	Endothelins (Endothelin)IBA 05/2008 - 01/2002
3	Endothelin-1 (Endothelin 1)IBA 09/2006 - 03/2001
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2006 - 11/2003
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 06/2002
2	Urea (Carbamide)FDA LinkGeneric 07/2015 - 10/2012
2	Notch3 ReceptorIBA 07/2015 - 11/2012
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 10/2012 - 12/2006
2	Collagen ReceptorsIBA 10/2012 - 12/2006
2	Tyrosine Kinase InhibitorsIBA 01/2012 - 05/2004
2	Nitric Oxide Synthase (NO Synthase)IBA 01/2011 - 01/2003
2	Angiotensin Receptors (Angiotensin II Receptor)IBA 07/2009 - 05/2003
2	Transforming Growth Factor beta (TGF-beta)IBA 09/2008 - 05/2003
2	Endothelin Receptors (Endothelin Receptor)IBA 05/2008 - 03/2001
2	Matrix Metalloproteinases (MMPs)IBA 07/2007 - 05/2003
2	Vasoconstrictor AgentsIBA 09/2006 - 04/2006
2	LuciferasesIBA 04/2006 - 01/2002
2	Captopril (Capoten)FDA LinkGeneric 11/2003 - 06/2002
2	Peptides (Polypeptides)IBA 02/2003 - 01/2002
1	Semaphorins (Semaphorin)IBA 01/2022
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2022
1	Actins (F Actin)IBA 01/2022
1	Angiotensin Receptor AntagonistsIBA 01/2021
1	angiotensin I (1-7)IBA 01/2021
1	ChromatinIBA 01/2018
1	Antisense OligonucleotidesIBA 05/2017
1	OligodeoxyribonucleotidesIBA 02/2016
1	FibrinIBA 07/2015
1	aliskiren FDA Link 04/2013
1	Hydralazine (Apresoline)FDA LinkGeneric 04/2013
1	Antihypertensive Agents (Antihypertensives)IBA 04/2013
1	ioflupaneIBA 10/2012
1	Thrombospondin 1IBA 06/2012
1	bardoxoloneIBA 01/2012
1	AlbuminsIBA 01/2012
1	Losartan (Cozaar)FDA LinkGeneric 01/2012
1	ConnexinsIBA 07/2011
1	Fibronectins (Fibronectin)IBA 01/2011
1	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 01/2011
1	Epidermal Growth Factor (EGF)IBA 07/2009
1	Fibrillar CollagensIBA 09/2008
1	Protein Glutamine gamma Glutamyltransferase 2IBA 09/2008
1	Biomarkers (Surrogate Marker)IBA 07/2007
1	Arginine (L-Arginine)FDA Link 04/2006
1	Vasopressins (Vasopressin)IBA 11/2005
1	Gefitinib (Iressa)FDA Link 05/2004
1	Therapeutic UsesIBA 05/2004
1	EnzymesIBA 02/2004
1	CytokinesIBA 02/2004
1	SodiumIBA 11/2003

Therapy/Procedure

6	Therapeutics 11/2014 - 01/2008
1	Warm Ischemia 01/2022
1	Cell- and Tissue-Based Therapy (Cell Therapy) 06/2016
1	Extracorporeal Shockwave Therapy 06/2016
1	Ligation 02/2016
1	Aftercare (After-Treatment) 04/2013
1	Kidney Transplantation 02/2004